[Kvtkozi] kkk.

[Orvosi Könyvtár]

Kedves Kolléga/Nő!

TUDNÁ-E VALAKI KÜLDENI A TELJES CIKKET?

Eur J Ophthalmol 2009; 19: 369 - 375

Corneal endothelium in patients with diabetes mellitus: a historical cohort study
Radha Shenoy, Rajeev Khandekar, Alexander A. Bialasiewicz, Abdullah Al Muniri
Abstract


PURPOSE. Retinopathy is the major cause of ocular morbidity in patients with diabetes mellitus. Chronic yperglycemia spares no organ and can affect the morphology and function of the various corneal layers, ompromising its transparency. This study was conducted to associate the status of corneal endothelium to diabetes mellitus (DM) and identify risk factors of compromised corneal endothelium.
METHODS. A total of 220 eyes of randomly selected patients (110 diabetic and 110 nondiabetic) were subjected to detailed slitlamp and fundus evaluation. Corneal endothelial status was evaluated using the NidekR Confoscan 2. Cell density, percentage polymegathism, and pleomorphism were calculated. The findings in diabetic patients were compared to those without disease. The outcome was correlated to diabetic retinopathy (DR). The effects of hypertension, hyperlipidemia, age, gender, type, duration, glycemic control, and grades of DR was also considered.
RESULTS. The mean corneal endothelial cell density was -175 cells/mm2 (95% CI -317 to -33 cells/mm2) less in eyes of diabetic patients. The number of endothelial cells with polymegathism was significantly greater among eyes of diabetic patients. There were less corneal endothelial cells with pleomorphism in nondiabetic patients. Polymegathism and pleomorphism of corneal endothelial cells seems to be positively associated with DM type II. Cell density was significantly lower in eyes with DR than those without DR.
CONCLUSIONS. Corneal endothelium in diabetic patients seems to be compromised. Evaluation
of corneal endothelium should be part of protocol for eye care of diabetic patients.



Köszönettel: Bede Józsefné Gyöngyvér 
         Ny9 << Szabolcs-Szatmár-Bereg Megyei Önkormányzat
                     Jósa András Oktató Kórház
                     Kállay Rudolf Orvostudományi Szakkönyvtár
                     4400 Nyíregyháza Szent István u. 68. Pf. 159.
                     Tel:  06-42-599-700 és 599-800/1392
                     Fax: 06-42-461-174
                     medlib at josa.hu
 
--------- következő rész ---------
Egy csatolt HTML állomány át lett konvertálva...
URL: http://lists.bibl.u-szeged.hu/pipermail/kvtkozi/attachments/20090716/4d885cb8/attachment.htm