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<DIV><FONT face=Arial size=2>Kedves Kolléga/Nő!</FONT></DIV>
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<DIV><FONT face=Arial size=2><U><STRONG>TUDNÁ-E VALAKI KÜLDENI A TELJES
CIKKET?</STRONG></U></FONT></DIV><FONT face=Arial size=2>
<DIV><BR><U><STRONG>Eur J Ophthalmol 2009; 19: 369 - 375<BR></DIV></STRONG></U>
<DIV class=Title hasbox="2">
<H3 hasbox="2">Corneal endothelium in patients with diabetes mellitus: a
historical cohort study<BR><A title=""
href="http://www.eur-j-ophthalmol.com/public/EJO/Article/Articleabstract.aspx?UidArticle=5DC873FA-8E2D-48E5-B22A-A1191D2F84C0&t=EJO#"
hasbox="1" windowLock="true" delay="0" fadespeed="0.04" offX="10" offY="10"
absY="NaN" absX="NaN" fixY="NaN" fixX="NaN" IEbugfix="false" boCSSHDR boCSSBDY
boBDY="Department of Ophthalmology, SQU Hospital, College of Medicine & Health Sciences, Al Khoud - Oman"
boHDR="Radha Shenoy" fade="false">Radha Shenoy</A>, <A title=""
href="http://www.eur-j-ophthalmol.com/public/EJO/Article/Articleabstract.aspx?UidArticle=5DC873FA-8E2D-48E5-B22A-A1191D2F84C0&t=EJO#"
hasbox="1" windowLock="true" delay="0" fadespeed="0.04" offX="10" offY="10"
absY="NaN" absX="NaN" fixY="NaN" fixX="NaN" IEbugfix="false" boCSSHDR boCSSBDY
boBDY="Eye Health Care, Directorate General of Health Affairs, Ministry of Health - Oman"
boHDR="Rajeev Khandekar" fade="false">Rajeev Khandekar</A>, <A
title="header=[Alexander A. Bialasiewicz] body=[Department of Ophthalmology, SQU Hospital, College of Medicine & Health Sciences, Al Khoud - Oman]"
href="http://www.eur-j-ophthalmol.com/public/EJO/Article/Articleabstract.aspx?UidArticle=5DC873FA-8E2D-48E5-B22A-A1191D2F84C0&t=EJO#">Alexander
A. Bialasiewicz</A>, <A
title="header=[Abdullah Al Muniri] body=[Department of Epidemiology & Medical Statistics, College of Medicine & Health Sciences, Al Khoud - Oman ]"
href="http://www.eur-j-ophthalmol.com/public/EJO/Article/Articleabstract.aspx?UidArticle=5DC873FA-8E2D-48E5-B22A-A1191D2F84C0&t=EJO#">Abdullah
Al Muniri</A></H3></DIV>
<DIV class=Abstract hasbox="2"><B class=azzurro hasbox="2">Abstract</B><BR><BR>
<P hasbox="2">PURPOSE. Retinopathy is the major cause of ocular morbidity in
patients with diabetes mellitus. Chronic yperglycemia spares no organ and can
affect the morphology and function of the various corneal layers, ompromising
its transparency. This study was conducted to associate the status of corneal
endothelium to diabetes mellitus (DM) and identify risk factors of compromised
corneal endothelium.<BR>METHODS. A total of 220 eyes of randomly selected
patients (110 diabetic and 110 nondiabetic) were subjected to detailed slitlamp
and fundus evaluation. Corneal endothelial status was evaluated using the Nidek®
Confoscan 2. Cell density, percentage polymegathism, and pleomorphism were
calculated. The findings in diabetic patients were compared to those without
disease. The outcome was correlated to diabetic retinopathy (DR). The effects of
hypertension, hyperlipidemia, age, gender, type, duration, glycemic control, and
grades of DR was also considered.<BR>RESULTS. The mean corneal endothelial cell
density was –175 cells/mm2 (95% CI –317 to –33 cells/mm2) less in eyes of
diabetic patients. The number of endothelial cells with polymegathism was
significantly greater among eyes of diabetic patients. There were less corneal
endothelial cells with pleomorphism in nondiabetic patients. Polymegathism and
pleomorphism of corneal endothelial cells seems to be positively associated with
DM type II. Cell density was significantly lower in eyes with DR than those
without DR.<BR>CONCLUSIONS. Corneal endothelium in diabetic patients seems to be
compromised. Evaluation<BR>of corneal endothelium should be part of protocol for
eye care of diabetic patients.</P></DIV>
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<DIV>Köszönettel: Bede Józsefné Gyöngyvér
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